We are currently working with RoadRunner (formerly Time Warner, AOL) service provider in United States, they are experiencing issues with their SMTP servers and randomly rejecting SMTP traffic. Currently mail is flowing through but some is bouncing back from them due to a reason they are still trying to narrow down. We will update when we have further information or a resolution.
This issue affects our entire global network, and some external sites we have tested.
Update: 6:34 PM EST: Even though we have not been officially updated, the problems with RoadRunner appear to have been resolved.